NUTRITIONAL STATUS OF PRETERM AND SMALL FOR GESTATIONAL AGE CHILDREN

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Abstract

Background: Preterm and small for gestational age (SGA) remain significant public health concerns worldwide. Objectives: We investigated the nutritional status of preterm and SGA children compared with term appropriate for gestational age (AGA) children from birth to 10-11 years. Methods: Children born to women who participated in a double-blinded randomized controlled trial of preconception micronutrient supplementation in Vietnam were classified into three groups: preterm AGA (n = 130), full-term SGA (n = 165) and full-term AGA (n = 1072). Anthropometric data (weight and height) were collected prospectively at birth, 3, 6, 12, 18, 24 months and at 6-7 and 10-11 years. Results: The mean gestational age was 34.9, 39.5 and 40.5 weeks for preterm, AGA and SGA infants, respectively. The rates of underweight were consistently higher in the SGA group in all periods. Preterm children consistently exhibited a higher rate of underweight compared to AGA children from birth through 6-7 years of age. Compared with AGA children, SGA children had a lower prevalence of overweight/obesity across all stages. Conclusions: Compared with AGA children, SGA children have higher rates of underweight and stunting. While preterm children have higher rates of malnutrition in early life, by adolescence their rates of overweight and obesity exceed those of AGA children.

https://doi.org/10.66517/jstmp.2025.5.8
Published 2025-12-31
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Issue Vol. 4 No. 5 (2025)
Section Original article
DOI 10.66517/jstmp.2025.5.8
Keywords Trẻ sinh non, Nhẹ cân so với tuổi thai, Nhẹ cân, Thừa cân/Béo phì, Thấp còi Preterm, Small for gestational age, Underweight, Overweight/Obesity, Stunting

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1.
Nguyen, P. T., Nguyen, S. V., Nguyen, H. T. X., Le, D. T. K. & Nguyen, T. T. NUTRITIONAL STATUS OF PRETERM AND SMALL FOR GESTATIONAL AGE CHILDREN. Tạp chí Khoa học và Công nghệ Y Dược 4, 122–134 (2025).

Chawanpaiboon S, Vogel JP, Moller AB, Lumbiganon P, Petzold M, Hogan D, et al. Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis. Lancet Glob Health. 2019;7(1):e37-e46. doi:10.1016/S2214-109X(18)30451-0.

Lawn JE, Ohuma EO, Bradley E, Idueta LS, Hazel E, Okwaraji YB, et al. Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting. Lancet. 2023;401(10389):1707-1719. doi:10.1016/S0140 -6736(23)00522-6.

Lee AC, Katz J, Blencowe H, Cousens S, Kozuki N, Vogel JP, et al. National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010. Lancet Glob Health. 2013;1(1):e26-36. doi:10.1016/S2214-109X(13) 70006-8.

Lee AC, Blencowe H, Lawn JE. Small babies, big numbers: global estimates of preterm birth. Lancet Glob Health. 2019;7(1):e2-e3. https:// www.thelancet.com/journals/langlo/article/ PIIS2214-109X(18)30484-4/fulltext.

Nguyen PH, Lowe AE, Martorell R, Nguyen H, Pham H, Nguyen S, et al. Rationale, design, methodology and sample characteristics for the Vietnam pre-conceptual micronutrient supplementation trial (PRECONCEPT): a randomized controlled study. BMC Public Health. 2012;12(1):898. doi:10.1186/1471-2458-12-898.

Cogill B. Anthropometric Indicators Measurement Guide. Washington (DC): Food and Nutrition Technical Assistance Project, Academy for Educational Development; 2003.

INTERGROWTH-21ˢᵗ. Postnatal Growth of Preterm Infants [Internet]. Available from: https://intergrowth21.tghn.org/postnatal-growth-preterm-infants/.

World Health Organization. The WHO Child Growth Standards [Internet]. 2010. Available from: http://www.who.int/childgrowth/standards/en/.

de Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J. Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ. 2007;85(9):660-667. doi:10.2471/BLT.07.043497.

Motte-Signoret E, Shankar-Aguilera S, Brailly- Tabard S, Soreze Y, Dell Orto V, Ben Ammar R, et al. Small for Gestational Age Preterm Neonates Exhibit Defective GH/IGF1 Signaling Pathway. Front Pediatr. 2021;9:711400. doi:10.3389/ fped.2021.711400.

Lee PA, Kendig JW, Kerrigan JR. Persistent short stature, other potential outcomes, and the effect of growth hormone treatment in children who are born small for gestational age. Pediatrics. 2003;112(1 Pt 1):150-162. doi:10.1542/peds.112.1.150.

Bortolotto CC, Santos IS, Dos Santos Vaz J, Matijasevich A, Barros AJD, Barros FC, et al. Prematurity and body composition at 6, 18, and 30 years of age: Pelotas (Brazil) 2004, 1993, and 1982 birth cohorts. BMC Public Health. 2021;21(1):321. doi:10.1186/s12889-021-10368-w.

Kerkhof GF, Willemsen RH, Leunissen RW, Breukhoven PE, Hokken-Koelega AC. Health profile of young adults born preterm: negative effects of rapid weight gain in early life. J Clin Endocrinol Metab. 2012;97(12):4498-4506. doi:10. 1210/jc.2012-1716.