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Abstract
Background: The imbalance between the body’s oxygen supply and demand is one of the causes leading to some complications in resuscitation after congenital heart surgery. A low ScvO2 is one of the valuable indicators predicting some major events after congenital open heart surgery. Objectives: Evaluate the value of ScvO2 in predicting MAE in children with congenital heart disease at the Vietnam National Children’s Hospital in 2022 - 2023. Methods: A cross-sectional and descriptive study was conducted on 117 children with congenital heart disease undergoing open heart surgery to describe the distribution of the value of ScvO2 according to time, weight, RACHS-1 score, time of aortic clamp and time of cardiopulmonary bypass at 4 times: immediately after leaving the Surgical Cardiac Intensive Care Unit (T1), after 6h (T2), after 12h (T3), after 24h (T4); Predictive ability of ScvO2 for some major adverse events (MAE) after open heart surgery in children with congenital heart disease. Results: The value of ScvO2 dropped to its minimum level after 6 hours of admission to the Surgical Cardiac Intensive Care Unit (54.42 ± 12.76%) and gradually increased at T3 and T4. The difference between times was statistically significant with p < 0.01. The proportion of study patients with MAE was 24.8%. The value of ScvO2 after 6 hours of admission to the post-operative Surgical Cardiac Intensive Care Unit, with a cut-off point of 54.5%, had the best ability to predict MAE during the study times. Sensitivity is 93.1%, while specificity is 69.3%, and the area under the curve AUC was 0.879. Conclusions: ScvO2 ≤ 54.5% at time T2 can predict MAE after open heart surgery in children with congenital heart disease, with very good AUC, specificity, and sensitivity.
| Published | 2025-12-31 | |
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| Issue | Vol. 4 No. 5 (2025) | |
| Section | Original article | |
| DOI | 10.66517/jstmp.2025.5.1 | |
| Keywords | ScvO2, MAE, Phẫu thuật tim mở ScvO2, MAE, Congenital open heart surgery |
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Rocha VHS, Manso PH, Carmona F. Central venous oxygen saturation/lactate ratio and prediction of major adverse events after pediatric heart surgery. Braz J Cardiovasc Surg. 2021;36(6):736–742. DOI: 10.21470/1678-9741- 2020-0521.
Seear MD, Scarfe JC, LeBlanc JG. Predicting major adverse events after cardiac surgery in children. Pediatr Crit Care Med. 2008;9(6):606– 611. DOI: 10.1097/PCC.0b013e31818d1971.
Ranucci M, et al. Central venous oxygen saturation and blood lactate levels during cardiopulmonary bypass are associated with outcome after pediatric cardiac surgery. Crit Care. 2010;14(4):R149. DOI:10.1186/cc9217.
Murni IK, et al. Outcome of pediatric cardiac surgery and predictors of major complication in a developing country. Ann Pediatr Cardiol. 2019;12(1):38–44. doi:10.4103/apc.APC_146_17.
Carmona F, Manso PH, Vicente WVA, Castro M, Carlotti APCP. Risk stratification in neonates and infants submitted to cardiac surgery with cardiopulmonary bypass: a multimarker approach combining inflammatory mediators, N-terminal pro-B-type natriuretic peptide and troponin I. Cytokine. 2008;42(3):317–324. doi:10.1016/j. cyto.2008.03.005.
Taiana M, et al. Analysis of Pv–aCO2/Ca–vO2 ratio and other perfusion markers in a population of 98 pediatric patients undergoing cardiac surgery. J Clin Med. 2023;12(17):5700. DOI: 10.3390/ jcm12175700.
Hirai N, et al. Association between regional oxygen saturation and central venous saturation in pediatric patients undergoing cardiac surgery: a prospective observational study. Pediatr Anesth. 2023;33(9):913–922. DOI: 10.1111/pan.14741.
Iliopoulos I, et al. Pre-operative neutrophil– lymphocyte ratio predicts low cardiac output in children after cardiac surgery. Cardiol Young. 2020;30(4):521–525. DOI: 10.1017/ S1047951120000487.
Abdelaziz AA, ElGendy FM, Hegazy AA, Hussein M, Ghazy RM. Prognostic value of combined central venous oxygen saturation and lactate in pediatric patients after cardiac surgery. Egypt Pediatr Assoc Gaz. 2023;71:84. DOI:10.1186/ s43054-023-00230-6.