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Abstract
Background: Research on the factors associated with hypoglycemia in low birth weight infants in Thai Nguyen is limited. This study aims to provide clinicians with more insight into preventing of early hypoglycemia in this population. Objective: To identify factors associated with hypoglycemia in low birth weight infants at the Neonatal-Pediatric Emergency Department, Thai Nguyen Central Hospital. Methods: A cross-sectional descriptive study was conducted on 175 low birth weight infants treated at the Neonatal-Pediatric Emergency Department of Thai Nguyen Central Hospital from August 2023 to August 2024. Results: Among the 175 low birth weight infants studied, 52.6% were male and 47.4% were female. The majority of low birth weight infants were preterm (86.9%). The mean gestational age was 33.82 ± 2.83 weeks, and the mean birth weight was 1929.59 ± 436.59 grams. The incidence of hypoglycemia was 65.1%. Univariate analysis identified several factors associated with hypoglycemia, including prematurity, multiple pregnancies (twins), and maternal weight gain greater than 12 kg during pregnancy. In the multivariate analysis, prematurity was associated with hypoglycemia in low birth weight infants (OR = 2.89; 95% CI: 1.14 - 7.32). Conclusions: The incidence of hypoglycemia in low birth weight infants was 65.1%, with prematurity being independently associated with hypoglycemia.
| Published | 2025-03-28 | |
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| Issue | Vol. 4 No. 1 (2025) | |
| Section | Original article | |
| DOI | 10.66517/jstmp.2025.1.7 | |
| Keywords | Hạ đường máu, Sơ sinh nhẹ cân, Non tháng Hypoglycemia, Low birth weight, Prematurity |
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World Health Organization. Low birthweight prevalence, <https://www.who.int/data/gho/ data/indicators/indicator-details/GHO/low-birth-weight-prevalence->(2024).
Nguyễn Thị Thanh Bình & Võ Ngọc Việt. Nghiên cứu tình trạng hạ đường máu ở trẻ sơ sinh bệnh lý có cân nặng thấp. Tạp chí Y học Việt Nam 524, 219-222 (2023).
Hoàng Thị Trang & Hoàng Thị Thủy Yên. Nghiên cứu đặc điểm lâm sàng và một số yếu tố liên quan đến tình trạng hạ đường máu ở trẻ sơ sinh nhẹ cân. DEMACVN - Nội tiết và Đái tháo đường 33, 4 (2020).
Adnyana, M. L. D. & al. Mortality of Neonatal Sepsis with Abnormal Blood Glucose Level. American Journal of Pediatrics 7, 9-13 (2021).
World Health Organization, “UNICEF-WHO low birthweight estimates: levels and trends 2000- 2015,” (2019).
WHO, “Assessment, Findings and Management - Low Blood Glucose,” in Managing Newborn Problems: A guide for doctors, nurses and midwives, F91 - F92 (2003).
Dr. Krina, Patel, P. & Maru, B. Hypoglycemia in exclusively breastfed low birth weight neonates. International Journal of Scientific Research 12, 4-6 (2023).
Thompson-Branch, A. & Havranek, T. Neonatal hypoglycemia. Pediatrics in review 38, 147-157 (2017).
Trần Thị Anh Thương, Bùi Văn Đức & Nguyễn Phú Đạt. Một số yếu tố liên quan đến hạ glucose máu ở trẻ sơ sinh tại Khoa Nhi - Bệnh viện Bạch Mai. Tạp chí Y học Việt Nam 520 (2022).
Bromiker, R. & al. Early neonatal hypoglycemia: incidence of and risk factors. A cohort study using universal point of care screening. The Journal of Maternal-Fetal & Neonatal Medicine 32, 786- 792 (2019).
Trần Thị Thu Hà. Nghiên cứu đặc điểm dịch tễ học lâm sàng và một số yếu tố liên quan đến hạ gluocse máu ở trẻ sơ sinh, Luận văn bác sĩ chuyên khoa II, trường Đại học Y Hà Nội (2015).
Trần Minh Tưởng & Lê Lý Hạ Liên. Các yếu tố nguy cơ liên quan đến hạ đường huyết ở trẻ sơ sinh non tháng tại Bệnh viện Sản - Nhi An Giang. Tạp chí Y học Việt Nam 532 (2023).
Arimitsu, T. & al. Risk factors of neonatal hypoglycemia in neonates born to mothers with gestational diabetes. Endocrine journal 70, 511- 517 (2023).
Sertsu, A. & al. Determinants of neonatal hypoglycemia among neonates admitted at Hiwot Fana Comprehensive Specialized University Hospital, Eastern Ethiopia: A retrospective cross-sectional study. SAGE Open Medicine 10, 20503121221141801 (2022).
Ibsa, S. & al. Hypoglycemia and Associated Factors among Neonates Admitted to Neonatal Intensive Care Unit in Eastern Ethiopia. East African Journal of Health and Biomedical Sciences 7, 13-24 (2023).